Specific Demonstration of the Human Hypophyseal Cells Which Produce Adrenocorticotropic Hormone
نویسندگان
چکیده
منابع مشابه
Ultracentrifugation of hypophyseal growth hormone.
Sedimentation velocity was measured in a Spinco ultracentrifuge’ operating at 165,000 X g. The hormone solutions (0.5 per cent) were prepared with borate buffer of pH 9.7 or saline at pH 9.1. Table I presents a typical run in a borate buffer; the sedimentation velocity constant was calculated by the procedure described by Svedberg and Pedersen (3). It may be noted that the individual values of ...
متن کاملThe Hypophyseal Growth Hormone, Nature and Actions
many formulae and figures. Its many chapter subheadings give the book its rather terse, outline form. A discussion of methods of isolation, characterization, and determination of purity is followed by successive chapters dealing with reaction rates as a function of substrate concentration, inhibitor action, temperature, and pH. Thermodynamic concepts are well developed in chapters on energetics...
متن کاملAdrenocorticotropic action of antidiuretic hormone.
By means of direct arterial perfusion of the adrenal glands of the hypophysectomized dog, it has been shown that synthetic lysine, arginine and acetyl arginine vasopressins stimulate the adrenal cortex directly to secrete hydrocortisone. Pressor activity and cortisol-stimulating activity were demonstrated to be independent of each other. Similar polypeptides, such as oxytocin, insulin, glucagon...
متن کاملAdrenocorticotropic Action of Antidiuretic Hormone
By means of direct arterial perfusion of the adrenal glands of the hypophysectomized dog, it has been shown that synthetic lysine, arginine and acetyl arginine vasopressins stimulate the adrenal cortex directly to secrete hydrocortisone. Pressor activity and cortisol-stimulating activity were demonstrated to be independent of each other. Similar polypeptides, such as oxytocin, insulin, glucagon...
متن کاملSedimentation behavior of hypophyseal growth hormone.
In a previous publication, it was reported that solution of the hypophyseal growth hormone in acetate buffers results in an increment of its intrinsic viscosity with an accompanying increase of molecular weight (1). Later, Smith et al. (2) confirmed these observations in ultracentrifugal studies. The purpose of this present investigation has been to study the sedimentation behavior of the hormo...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 1970
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem-31-4-347